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| Rank | Player | Opp | NFL Fantasy Experts |
|---|---|---|---|
| 1 | Israel Abanikanda RB - NYJ | IND | -- |
| 2 | Ameer Abdullah RB - LV | @MIA | -- |
| 3 | De'Von Achane RB - MIA | LV | -- |
| 4 | Salvon Ahmed RB - MIA Q | LV | -- |
| 5 | Rasheen Ali RB - BAL Q | @PIT | -- |
| 6 | Braelon Allen RB - NYJ | IND | -- |
| 7 | Tyler Allgeier RB - ATL | @DEN | -- |
| 8 | Tyler Badie RB - DEN | ATL | -- |
| 9 | Emani Bailey RB - KC | @BUF | -- |
| 10 | Saquon Barkley RB - PHI | WAS | -- |
| 11 | Nick Bawden RB - NYJ | IND | -- |
| 12 | Andrew Beck RB - HOU | @DAL | -- |
| 13 | Trey Benson RB - ARI | Bye | -- |
| 14 | Tank Bigsby RB - JAX | @DET | -- |
| 15 | Raheem Blackshear RB - CAR | Bye | -- |
| 16 | Khari Blasingame RB - CHI | GB | -- |
| 17 | Brandon Bolden RB - LV | @MIA | -- |
| 18 | Mike Boone RB - CAR | Bye | -- |
| 19 | Gary Brightwell RB - NYG Q | Bye | -- |
| 20 | British Brooks RB - HOU | @DAL | -- |
| 21 | Chris Brooks RB - MIA | LV | -- |
| 22 | Jonathon Brooks RB - CAR Q | Bye | -- |
| 23 | Brittain Brown RB - LV | @MIA | -- |
| 24 | Chase Brown RB - CIN | @LAC | -- |
| 25 | Spencer Brown RB - CAR Q View News | Bye | -- |
| 26 | Robert Burns RB - ATL | @DEN | -- |
| 27 | Noah Cain RB - CIN | @LAC | -- |
| 28 | Michael Carter RB - ARI | Bye | -- |
| 29 | Ty Chandler RB - MIN | @TEN | -- |
| 30 | Zach Charbonnet RB - SEA | @SF | -- |
| 31 | Nick Chubb RB - CLE Q | @NO | -- |
| 32 | Tarik Cohen RB | Bye | -- |
| 33 | Jack Colletto RB - PIT | BAL | -- |
| 34 | Chris Collier RB - BAL | @PIT | -- |
| 35 | James Conner RB - ARI | Bye | -- |
| 36 | Snoop Conner RB - DAL | HOU | -- |
| 37 | Dalvin Cook RB - BAL | @PIT | -- |
| 38 | James Cook RB - BUF | KC | -- |
| 39 | Jashaun Corbin RB - NYG | Bye | -- |
| 40 | Blake Corum RB - LA | @NE | -- |
| 41 | DeeJay Dallas RB - ARI | Bye | -- |
| 42 | Isaiah Davis RB - NYJ | IND | -- |
| 43 | Malik Davis RB - DAL | HOU | -- |
| 44 | Ray Davis RB - BUF | KC | -- |
| 45 | Tyrion Davis-Price RB - PHI | WAS | -- |
| 46 | Emari Demercado RB - ARI | Bye | -- |
| 47 | AJ Dillon RB - GB | @CHI | -- |
| 48 | Gerrid Doaks RB | Bye | -- |
| 49 | J.K. Dobbins RB - LAC Q | CIN | -- |
| 50 | Elijah Dotson RB - LAC | CIN | -- |
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